Megamentin 625 mg 6s tablet salt information:
Uses of Megamentin 625 mg Tablet 6s:
Amoxicillin is a penicillin antibiotic that fights bacteria. Amoxicillin is used to treat many different types of infections caused by bacteria, such as tonsillitis, bronchitis, pneumonia, gonorrhea and ear, nose, throat, skin or urinary tract infections.
Side Effects of Megamentin 625mg Tablet 6s:
Nausea, vomiting, diarrhea, indigestion, rash and hives, candida superinfection. Potentially Fatal: Anaphylactic reaction with CV Collapse Esp with parenteral use.
Drug interactions of Megamentin 625 mg Tablet 6s:
Allopurinol may reduce the renal tubular secretion of amoxicillin thereby increasing the serum levels of amoxicillin. Concomitant use can reduce the effectiveness of oral contraceptives.
Contraindications of Megamentin 625 mg Tablet 6s:
Allergy to penicillin.
Mechanism of action of Megamentin 625 mg Tablet 6s:
Clavulanic acid has a high affinity and binds to certain Β-lactamases which generally inactivate amoxicillin by hydrolyzing its Β-lactam ring. The combination of potassium clavulanate with amoxicillin extends the antibacterial spectrum of amxicillin to include many bacteria normally resistant to amoxicillin and other penicillins and cephalosporins. Distribution: protein bonds: about 25% (clavulanic acid); About 18% (Amoxicillin). Amoxicillin is easily distributed in most tissues and body fluids, with the exception of the brain and spinal fluid. Excretion: half-life after oral administration: 1.3 hours (amoxicillin); 1 hour (clavulanic acid). About 50-70% of Amoxicillin and 25-40% of clavulanic acid are excreted unchanged in the urine during the first 6 hours after surgery.
Special precautions for Megamentin 625 mg Tablet 6s:
History of allergy especially to cephalosporins, infectious mononucleosis, severe renal insufficiency.