Boldebolin (Alpha Pharma) 10amps 250mg / 1ml
Equipoise overview and history
Equipoise is the brand / trade name for the anabolic steroid Boldenone, which is an oil-based injectable steroid with the Undecylenate ester attached to it for a sustained release rate and half-life. It is a derivative of testosterone which maintains the anabolic strength of testosterone but exhibits a reduced androgenic effect in comparison. Equipoise is primarily a veterinary product, originally intended for use in animals. Equipoise has gained popularity with bodybuilders and athletes as a less androgenic form of testosterone with less estrogenic activity than testosterone as well. Many users prefer to compare it to that of nandrolone (Deca Durabolin), however, this comparison is very poor as nandrolone exhibits different properties than Equipoise and is also a completely different class of compounds (a 19-nor, also known as a progestin) . However, many consider Nandrolone and Equipoise to be a solid substitute for each other in a given cycle.
Some interesting facts about this compound earlier: Equipoise was in fact developed in 1949, even before Dianabol (Methandrostenolone), making Equipoise technically the first synthetic derivative of testosterone even before Dianabol was ever thought of. Furthermore, Dianabol itself is actually Equipoise (Boldenone) with a methyl group attached to its 17-beta hydroxyl group on the steroid chemical structure (also known as C17-alpha alkylation) in order to allow it to become orally bioavailable in the body. Technically, Dianabol (Methandrostenolone) is actually Equipoise C17-alpha alkylated. It would have been considered an oral form of Equipoise, but methylation at the seventeenth carbon changed enough properties of the compound that it was considered a totally different anabolic steroid analog, and called Methandrostenolone (Dianabol). If the images of the chemical structures of Equipoise and Dianabol were arranged side by side, one would easily be able to distinguish the same chemical structure between the two, with the exception of the methyl group affixed to the 17th carbon on the chemical structure of Dianabol. . It is very evident that these two anabolic steroids are essentially the exact same.
Although Equipoise was first developed in 1949, it wasn't until 1960 when this compound would finally be released and marketed as Parenabol. Between 1949 and its release in the 1960s, Ciba had fun with Equipoise by trying to put different esters on it in order to increase its half-life and release rates. The final conclusion was that it would be released with the Undecylenate ester attached to it, and the final preparation was that of Boldenone Undecylenate. Following the release of Parenabol, various clinical studies and tests of this compound were conducted in the late 1960s and early 1970s with the aim of using it as lean mass to promote and preserve the anabolic steroid in order to to treat people suffering from any condition such as weight loss and weight loss were symptoms, as well as an osteoporosis treatment. Parenabol saw very little application or use after its release, and in the late 1970s it was removed from the market and discontinued.
Squibb will then collect the patents for this anabolic steroid and release Boldenone under the name Equipoise as a veterinary anabolic steroid intended primarily for application in horses, but is also intended for use in other animals. Equipoise is well known for its increased lean mass as well as its appetite-stimulating effects, which is a common effect among almost all anabolic steroids. However, Equipoise tends to stimulate appetite at much higher levels than any other anabolic steroid. Although Equipoise's manufacturing and marketing has changed many hands over the years, it still remains available on the American and international market with plenty of generic brands and current brands available.
Equipoise chemical characteristics
As mentioned above, Equipoise is a synthetic derivative of testosterone where it has been modified to carbon 1 and carbon 2 on the steroid structure, where double bonds have been added between these two carbon atoms. This is what is known as the modification that is responsible for reducing Equipoise's affinity for interaction with the aromatase enzyme (the enzyme responsible for the conversion of androgens into estrogens). Consequently, its estrogenic activity is considered lower than testosterone. Equipoise is Boldenone with the Undecylenate ester attached to it. Specifically, “Undecylenate” is undecylenoic acid, but when bound to Boldenone it is correctly referred to in chemistry as an ester bond (or ester bond). Undecylenoic acid is chemically linked to the 17-beta hydroxyl group on the Boldenone structure. The addition of this ester increases the release rate and the half-life of the hormone to favor a longer release window. The main reason for the increase in its half-life and release rate is due to the fact that once Boldenone Undecylenate enters the bloodstream, enzymes work to break the bond between the ester and the hormone, which requires an amount time variable. The end result is that of the ester being removed from the hormone by these enzymes, and the result that follows is pure Boldenone free to do its job in the body. This process of enzymes that remove the ester from the hormone to which it is attached is what is responsible for the slower release rates. When the Undecylenate ester is linked to Boldenone, creating Boldenone Undecylenate, the half-life of Boldenone is now extended to 14 days, providing a slower release and hormone activity than the hormone otherwise without this ester.
Also, as noted near the beginning of this section, Equipoise and Dianabol are structurally identical with the only difference between the two being that Equipoise contains an Undecylenate ester linked to its 17-beta hydroxyl group, and Dianabol instead contains a linked methyl group. a its 17-beta hydroxyl group. Dianabol contains the methyl group (also known as C17-alpha alkylation) to prevent it from being metabolized and broken down by the liver by oral ingestion. Aside from these changes, the two hormones are exactly identical and would be considered to be exactly the same compounds. However, both of these hormones act significantly differently from each other in the body, which is a very strong indication that the addition of a methyl group (C17-alpha alkylation) to the 17th carbon not only affects the resistance of the Breaking hormone in the liver – it actually changes the effects and properties of the anabolic steroid.
Being a derivative of testosterone equals it confers many of the same properties. First of all, it has the exact same anabolic resistance value (100) and is also an aromatizable anabolic steroid, which means that Equipoise can and does convert into estrogen in the body through interaction with the aromatase enzyme. However, its double bond modifications between carbons 1 and 2 reduce its affinity for the aromatase enzyme, ensuring a lower aromatization rate and therefore a lower estrogenic activity in the body.
This means that Equipoise will still be converted to estrogen, but in much less significant amounts than its parent hormone Testosterone. While this is a very comforting fact and a pleasant property, the problem of estrogenic side effects is still a problem and should not be ignored by any user. Therefore, individuals cannot expect an elimination of potential water retention, but a big difference in a reduction from Equipoise alone. Although at reasonable and moderate dosages, Equipoise should not show swelling or other estrogenic effects (depending on the user's sensitivity), the risk of these estrogenic side effects will actually increase when higher and higher doses of Equipoise are used. Increasing the doses will mean an increase in the aromatization rates of the anabolic steroid into estrogen.
Equipoise itself possesses a low androgenic strength score (lower than its parent hormone Testosterone), which should be liked by individuals who are sensitive to any number of androgenic side effects. Overall, people using Equipoise can expect the same anabolic size, strength, and mass gains that would come from testosterone with a lower incidence of estrogenic activity and androgenic side effects. This means that the gains from Equipoise itself should, for the most part, be fairly solid lean mass gains with minimal water retention (depending on the dose) and would be a perfect addition to any bulking or lean mass cycle. It would also work as an appropriate substitute for nandrolone in any stack.